Pill with imprint CECLOR CD mg is Blue, Elliptical / Oval and has been identified as Ceclor CD mg. cefaclor tablets 375mg It is supplied by Elan Pharmaceutical/Athena Neurosciences Inc.
Nursing Mothers No studies in lactating women have been performed with cefaclor extended-release tablets. The effect on nursing infants is not known.
Caution should be exercised when cefaclor extended-release tablets are administered to a nursing woman. Pediatric Use Safety and effectiveness of cefaclor extended-release tablets in pediatric patients less than 16 years of age have not been established. These differences are considered to be primarily a result of age-related decreases in renal function. In clinical studies when geriatric patients received the usual recommended adult doses, clinical efficacy and safety were comparable to results in non-geriatric adult patients.
Nausea and vomiting have been reported rarely. As with some penicillins and some other cephalosporins, transient hepatitis and cholestatic jaundice have been reported rarely.
Other effects considered related to therapy included eosinophilia 1 in 50 patients , genital pruritus, moniliasis or vaginitis about 1 in 50 patients , and, rarely, thrombocytopenia or reversible interstitial nephritis. Causal Relationship Uncertain CNS -- Rarely, reversible hyperactivity , agitation, nervousness, insomnia, confusion , hypertonia , dizziness, hallucinations , and somnolence have been reported.
Transitory abnormalities in clinical laboratory test results have been reported. Although they were of uncertain etiology , they are listed below to serve as alerting information for the physician. Renal -- Slight elevations in BUN or serum creatinine less than 1 in or abnormal urinalysis less than 1 in Cephalosporin-class Adverse Reactions In addition to the adverse reactions listed above that have been observed in patients treated with cefaclor, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics: Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment when the dosage was not reduced.
If seizures associated with drug therapy occur, the drug should be discontinued. There have been reports of increased anticoagulant effect when cefaclor and oral anticoagulants were administered concomitantly. Antibiotics, including cefaclor, should be administered cautiously to any patient who has demonstrated some form of allergy , particularly to drugs.
Clostridium difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including Cefaclor for Oral Suspension, USP, and may range in severity from mild diarrhea to fatal colitis. Therefore antacids should not be taken right before or at the same time as cefaclor. Sustained release is useful with Cefaclor as it has a very short half-life. Blood transfusions are the 1 passer of this drug. It is based on the various factors like body weight, age, sex, and medical condition of the patient.
The dose range of Cefaclor is solely decided by your pharmacist. Consume the medicine daily, at the same interval of time. Get your prescription refilled, before you run out of the drug completely. Do not stop taking the medicine suddenly. Stopping the medicine suddenly may reverse your improving condition. Although animal studies have shown no evidence of impaired fertility or harm to the foetus due to cefaclor, there are no adequate and well-controlled studies in pregnant women.
Cefaclor MR should be used during pregnancy only if clearly needed. Usage in nursing mothers: Small amounts of cefaclor have been detected in breast milk following administration of single mg doses. Average levels of about 0. Trace amounts were detected at one hour.
As the effect on nursing infants is not known, caution should be exercised when cefaclor is administered to a nursing woman. Ethinyl Estradiol; Norethindrone Acetate: Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate: Ethinyl Estradiol; Norethindrone; Ferrous fumarate: Moderate Closely monitor for cefaclor-induced side effects such as nausea, diarrhea, or abdominal pain when these drugs are used together.
In some patients, a dosage reduction of cefaclor may be required. Following oral administration, leflunomide is metabolized to an active metabolite, teriflunomide, which is responsible for essentially all of leflunomide's in vivo activity. Teriflunomide is an inhibitor of the renal uptake organic anion transporter OAT3. Use of teriflunomide with cefaclor, a substrate of OAT3, may increase cefaclor plasma concentrations. Moderate Nephrotoxicity associated with cephalosporins may be potentiated by concomitant furosemide therapy.
Clinicans should be aware that this may occur even in patients with minor or transient renal impairment. Minor Probenecid competitively inhibits renal tubular secretion of cefaclor, thereby causing higher serum concentrations and prolonged elimination of cefaclor.
Keflor (375mg) (Cefaclor) Drug Price and Information
In clinical studies when geriatric patients received cefaclor usual recommended adult doses, cefaclor tablets 375mg, clinical efficacy and safety were comparable to results in non-geriatric adult patients. No dosage changes are recommended for healthy geriatric patients. 375mg of teriflunomide with cefaclor, a substrate of OAT3, may increase cefaclor plasma concentrations. Consider the benefits of breast-feeding, cefaclor tablets 375mg, the bactrim panic disorder of potential infant drug exposure, and cefaclor risk of an untreated or inadequately treated tablet. Inhibition of vitamin K synthesis due to alterations in the intestinal flora may be a mechanism; however, concurrent infection is also a tablet risk factor for elevated INR. Although they were of uncertain etiologythey are listed below to serve as alerting 375mg for the physician. In the UK, The Committee on the Safety of Medicines CSM has warned that the risk of diarrhea and rarely antibiotic-associated colitis are more likely with higher doses. Trace amounts tablet detected at 1 hour, cefaclor tablets 375mg. In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient. These studies have revealed no harm to the fetus due to cefaclor. Furunculosis and other skin structure infections. There are, however, cefaclor tablets 375mg, no adequate and well-controlled studies in pregnant women. Sustained release is useful cefaclor Cefaclor as it has a very short half-life. If superinfection occurs during therapy, 375mg measures should be taken. Lower urinary tract infections: If possible, avoid coadministration.
Ceclor CD Tablet, Extended Release 12 Hr
Pharyngitis and tonsillitis caused by Streptococcus pyogenes group A streptococci. If 375mg allergic reaction to cefaclor occurs, the drug should be discontinued and the patient treated with the appropriate agents. Since absorption is enhanced by administration with food, cefaclor tablets 375mg, Cefaclor MR should be taken with meals. Nausea and vomiting have been reported rarely. Ethinyl Estradiol; Norethindrone; Ferrous fumarate: No serious sequelae have been reported. Rare side effects include eosinophilia and blood disorders including thrombocytopenialeucopeniaagranulocytosisaplastic tablet and haemolytic anaemia ; reversible interstitial nephritis ; hyperactivitynervousnesssleep disturbances, hallucinationsconfusionhypertoniaand dizziness. In clinical trials, doses of 1. The frequency and severity of serum sickness -like reactions in children has led researchers to question its role in pediatric illness. If possible, avoid cefaclor. During long-term antibiotic administration, the risk for drug interaction with OCs is less clear, but alternative or additional contraception may be advisable in selected circumstances. Gram-positive coverage 375mg nonpencillinase- and pencillinase-producing Staphylococcus aureus methicillin-resistant strains are resistant and streptococci except enterococci. A small percentage is excreted in breast milk. Treatment with antibacterial agents alters the normal tablet cefaclor the colon leading to overgrowth of C.