In post-marketing experience, deaths have been reported with an overdose of methocarbamol alone or in the presence of other CNS depressants, alcohol or psychotropic drugs. Treatment Management of overdose includes symptomatic and supportive treatment. Supportive measures include maintenance of an adequate airway, monitoring urinary output and vital signs, and administration of intravenous fluids if necessary.
The usefulness of hemodialysis in managing overdose is unknown. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber. Pharmacokinetics In healthy volunteers, the plasma clearance of methocarbamol ranges between 0. Methocarbamol is metabolized via dealkylation and hydroxylation.
Conjugation of methocarbamol also is likely. Essentially all methocarbamol metabolites are eliminated in the urine. Tell your health care provider if you are taking any other medicines, especially any of the following: Anticholinesterases eg, neostigmine because their effectiveness may be decreased by Robaxin Sodium oxybate GHB because the risk of its side effects may be increased by Robaxin. This may not be a complete list of all interactions that may occur.
Ask your health care provider if Robaxin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Robaxin may cause drowsiness, dizziness, lightheadedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Robaxin with caution.
Do not drive or perform other possible unsafe tasks until you know how you react to it. Do not drink alcohol or use medicines that may cause drowsiness eg, sleep aids, muscle relaxers while you are using Robaxin; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Methocarbamol can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using this medicine. Methocarbamol is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures.
Follow your doctor's instructions. Store at methocarbamol room temperature away from moisture and heat. Dosage Information in more detail What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.
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