Decadron 4mg tablets
If you have diabetes , this drug may make it harder to control your blood sugar levels. Monitor your blood sugar levels regularly and inform your doctor of the results.
Your medicine, exercise plan , or diet may need to be adjusted. This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana. This medication may slow down a child's growth if used for a long time. Consult the doctor or pharmacist for more details. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Your dose needs may change due to surgery, illness, stress , or a medical emergency. Tell your doctor about any such situation that affects you. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine. Do not stop using dexamethasone suddenly, or you could have unpleasant withdrawal symptoms.
Ask your doctor how to safely stop using this medicine. In case of emergency, wear or carry medical identification to let others know you use this medicine.
Store at room temperature away from moisture and heat. What happens if I miss a dose? Call your doctor for instructions if you miss a dose of this medicine. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at An overdose of dexamethasone is not expected to produce life threatening symptoms. If steroid therapy is continued for more than 6 weeks, intraocular pressure should be monitored.
Information for Patients Patients should be warned not to discontinue the use of corticosteroids abruptly or without medical supervision. As prolonged use may cause adrenal insufficiency and make patients dependent on corticosteroids, they should advise any medical attendants that they are taking corticosteroids and they should seek medical advice at once should they develop an acute illness including fever or other signs of infection.
Following prolonged therapy, withdrawal of corticosteroids may result in symptoms of the corticosteroid withdrawal syndrome including, myalgia, arthralgia, and malaise. Persons who are on corticosteroids should be warned to avoid exposure to chickenpox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Aminoglutethimide may diminish adrenal suppression by corticosteroids. Amphotericin B Injection and Potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents e. In addition, there have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure.
Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance see Drug Interactions: Hepatic Enzyme Inducers, Inhibitors and Substrates. Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. If possible, anticholinesterase agents should be withdrawn at least 24 hours before initiating corticosteroid therapy.
Co-administration of corticosteroids and warfarin usually results in inhibition of response to warfarin, although there have been some conflicting reports. Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect.
Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. Serum concentrations of isoniazid may be decreased. Cholestyramine may increase the clearance of corticosteroids. Increased activity of both cyclosporine and corticosteroids may occur when the two are used concurrently. Convulsions have been reported with this concurrent use. False-negative results in the Dexamethasone suppression test DST in patients being treated with indomethacin have been reported.
Thus, results of the DST should be interpreted with caution in these patients. Patients on digitalis glycosides may be at increased risk of arrhythmias due to hypokalemia.
Ephedrine may enhance the metabolic clearance of corticosteroids, resulting in decreased blood levels and lessened physiologic activity, thus requiring an increase in corticosteroid dosage. Estrogens, Including Oral Contraceptives: Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. Hepatic Enzyme Inducers, Inhibitors and Substrates: Drugs which inhibit CYP 3A4 e. Dexamethasone is a moderate inducer of CYP 3A4.
Co-adminstration with other drugs that are metabolized by CYP 3A4 e. In addition, ketoconazole alone can inhibit adrenal corticosteroid synthesis and may cause adrenal insufficiency during corticosteroid withdrawal. Concomitant use of aspirin or other nonsteroidal antiinflammatory agents and corticosteroids increases the risk of gastrointestinal side effects.
Aspirin should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia. The clearance of salicylates may be increased with concurrent use of corticosteroids. In post-marketing experience, there have been reports of both increases and decreases in phenytoin levels with Dexamethasone co-administration, leading to alterations in seizure control.
Corticosteroids may suppress reactions to skin tests. Co-administration with thalidomide should be employed cautiously, as toxic epidermal necrolysis has been reported with concomitant use. Patients on corticosteroid therapy may exhibit a diminished response to toxoids and live or inactivated vaccines due to inhibition of antibody response. Corticosteroids may also potentiate the replication of some organisms contained in live attenuated vaccines.
Carcinogenesis, Mutagenesis, Impairment of Fertility No adequate studies have been conducted in animals to determine whether corticosteroids have a potential for carcinogenesis or mutagenesis.
Steroids may increase or decrease motility and number of spermatozoa in some patients. Corticosteroids have been shown to be teratogenic in many species when given in doses equivalent to the human dose. Animal studies in which corticosteroids have been given to pregnant mice, rats, and rabbits have yielded an increased incidence of cleft palate in the offspring.
There are no adequate and well-controlled studies in pregnant women. Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Infants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism. Nursing Mothers Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Because of the potential for serious adverse reactions in nursing infants from corticosteroids, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Pediatric Use The efficacy and safety of corticosteroids in the pediatric population are based on the well-established course of effect of corticosteroids, which is similar in pediatric and adult populations.
Other indications for pediatric use of corticosteroids, e. Like adults, pediatric patients should be carefully observed with frequent measurements of blood pressure, weight, height, intraocular pressure, and clinical evaluation for the presence of infection, psychosocial disturbances, thromboembolism, peptic ulcers, cataracts, and osteoporosis.
Pediatric patients who are treated with corticosteroids by any route, including systemically administered corticosteroids, may experience a decrease in their growth velocity. This negative impact of corticosteroids on growth has been observed at low systemic doses and in the absence of laboratory evidence of hypothalamic-pituitary-adrenal HPA axis suppression i.
Growth velocity may therefore be a more sensitive indicator of systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis function. The linear growth of pediatric patients treated with corticosteroids should be monitored, and the potential growth effects of prolonged treatment should be weighed against clinical benefits obtained and the availability of treatment alternatives.
Availability of Decadron Tablets Announced
Skin Tests Corticosteroids may suppress reactions to skin tests. Other reported clinical experience has not identified differences decadron responses between the elderly and younger patients. For greater accuracy, give 0. This drug may make you dizzy. The molecular formula is C22H29FO5. Also, existing emotional tablet or psychotic tendencies may be aggravated by corticosteroids. Fluid and Electrolyte Disturbances Congestive heart failure in susceptible patients, fluid retention, hypokalemic alkalosis, potassium 4mg, sodium retention. In addition, decadron 4mg tablets, the oral doxycycline 150mg contains the following inactive ingredients: Dermatologic Diseases Bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, and severe erythema multiforme Stevens-Johnson syndrome.
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Eighth Day Follow-up visit This schedule is designed to ensure adequate decadron during acute episodes, while minimizing the risk of overdosage in chronic cases. However, the response to such vaccines cannot be predicted. Immunization procedures may be undertaken in patients who are receiving corticosteroids as replacement therapy, decadron 4mg tablets, e. Nursing Mothers Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, 4mg cause other untoward effects. Thus, results of the DST should be interpreted with caution in these patients. Patients on digitalis glycosides may be at increased tablet of arrhythmias due to hypokalemia. Decadron have been shown to be teratogenic in many species when given in doses equivalent to the human dose. This is not a complete list of side effects and others may occur, decadron 4mg tablets. Their synthetic analogs including dexamethasone are 4mg used for their anti-inflammatory effects in disorders of many organ systems.