After its release, it became very popular. If used for a long period, it can cause dependence. Upon discontinuing its use, patients oftentimes experienced withdrawal and rebound symptoms including: Lorazepam, on the other hand, is distributed under the brand names Ativan and Temesta. It is also a drug of the benzodiazepine class which also has anxiolytic, amnesic, sedative, anticonvulsant, and muscle relaxant properties.
It was released in for the treatment of anxiety, insomnia, seizures, and to sedate hospitalized and aggressive patients. Like other benzodiazepine drugs, it is also short acting but has a higher potential for addiction and abuse. Because of its sedative, hypnotic, and amnesia properties, it is often used for criminal purposes.
Lorazepam use for a long period can cause tolerance, dependence, and mild cognitive impairment. Unlike Xanax, which can be used for up to eight weeks, Lorazepam can only be used for up to four weeks.
What are the side effects of alprazolam or lorazepam? Pretty much the same. Most are from nervous system depression, which causes cognitive dysfunction, depression, dizziness, drowsiness, dysarthria a motor speech disorder , fatigue, irritability, memory impairment, and sedation.
How fast do they work and how long do they last? There are some subtle differences between the two here. This is important if you are using them before getting on a plane, having a root canal, or getting into an MRI scanner. With alprazolam Xanax the onset of action for BOTH the immediate release and extended release formulations is 1 hour. Regular alprazolam will work for about 5 hours; extended release about 11 hours.
Lorazepam has a more rapid onset of action, 30 — 60 minutes, and may last up to 8 hours. Both are cleared by the liver, so they will last longer in folks with liver disease.
Xanax and Ativan tablets are both scored, so pill splitting is an option. Xanax can also be used to treat nausea that is arises due to chemotherapy. Alprazolam is the most common prescribed and misused benzodiazepine in US.
Alprazolam has shown side-effects such as disinhibition, change in libido, jaundice very rare , hallucinations rare , dry mouth infrequent , ataxia, slurred speech, suicidal ideation rare , urinary retention infrequent , skin rash, respiratory depression, constipation, anterograde amnesia, concentration problems, drowsiness, dizziness, lightheadedness, fatigue, unsteadiness, impaired coordination, and vertigo.
Since it is easy to become addicted to Alprazolam, withdrawal symptoms for the drug include anxiety, irritability, insomnia, sensory disturbances, mania, schizophrenia, seizure disorders and suicidal tendencies. Lorazepam is most commonly used for short-term treatment of anxiety, insomnia, acute seizures including status epilepticus and sedation. Lorazepam is said to have a high addictive potential and abuse potential due to its sedative-hypnotic and anterograde amnesia properties.
The US Food and Drug Administration advices that the drug should only be used for a short-term such as weeks, and prolonged use should be avoided. Due to it being fast acting, it useful in treating fast onset panic anxiety.
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